BA/SA/MA: Development of Acoustic Membranes for Dry-Coupled Ultrasound Detection in Non-Invasive Glucose Monitoring

29.07.2026, Abschlussarbeiten, Bachelor- und Masterarbeiten

As part of the Helmholtz-funded REVOPT project, we are developing a miniaturized detector for non-invasive biomarker monitoring based on optoacoustic mid-infrared spectroscopy.

In this project, the development of novel acoustic interfaces in ultrasound detection are the core element to make our detector applicable for reproducible non-invasive in-vivo sensing. You will investigate, fabricate, and characterize materials and structures with the goal of achieving low acoustic attenuation in the MHz frequency range, a smooth and broadband frequency response, and efficient acoustic coupling without the need for water or ultrasound gel. The outcome of your work will be directly used for the further development of our miniaturized detector for non-invasive biomarker monitoring.

Thesis Objectives

The goal of this thesis is to identify, fabricate, and evaluate materials, suitable for ultrasound detection under realistic measurement conditions. A particular focus will be placed on achieving reliable acoustic coupling while maintaining excellent acoustic performance. You will systematically characterize the acoustic and mechanical properties of different concepts, develop analysis tools for data evaluation, and assess their suitability for future biomedical applications. Ultimately, you will propose and validate new acoustic coupling solutions to address current challenges in ultrasound probes.

Tasks

• Literature research on materials, acoustic coupling strategies, and ultrasound detector technologies
• Design and fabrication of concepts and interfaces for ultrasound detection
• Development of a suitable characterization setup to measure acoustic, mechanical, and practical properties of fabricated interfaces
• Development of Python-based measurement and data analysis tools
• Structured analysis, documentation and presentation of results

Requirements

• Background in Biomedical Engineering, Chemistry, Materials Science, Mechanical Engineering, Mechatronics or a related field
• Experience working in a wet lab environment is beneficial
• Strong interest in material development and biomedical sensing
• Programming skills in Python
• Hands-on experience with laboratory experiments and prototype development
• Experience with polymers and biomaterials, material characterization, or ultrasound measurements is beneficial

What We Offer

• The opportunity to contribute to a cutting-edge, interdisciplinary research topic with real-world impact
• State-of-the-art laboratory equipment
• The freedom to shape the focus of the thesis according to your strengths and interests while receiving structured guidance and support
• Access to a state-of-the-art technology laboratory for simulation and experimental work
• Collaboration with a MedTech startup
• Flexible working conditions including a mix of on-site and remote work

Interested?

Send an e-mail including a letter of motivation, CV and your latest transcript of records to: maximilian.gotsch@tum.de

Kontakt: maximilian.gotsch@tum.de