Bachelor / Master thesis: Building a mechanistic model for a new chromatographic multi-column device

24.04.2024, Diplomarbeiten, Bachelor- und Masterarbeiten

Interested in modeling in the biotech world? We seek a motivated student at the Chair of Bioseparation Engineering in Garching.

The project: Building models has become an essential part of process development in the biotech industry. Process understanding and automation are advanced with these, while practical work can often be reduced. In this project, a model for purifying a tagged ligand will be designed and used for process automation. We apply a multi-column chromatography system (OCTAVE Bio, Tosoh). Your work will aim to characterize the system components and implement A mechanistic model in CADET, a Python-based application.

Your profile: - Student of Biotechnology or similar with modeling interests - Student of automation technologies or similar with biotech interest - Eager to learn new - Motivated to solve problems - Independent work style

Your tasks in short: - Characterize OCTAVE Bio with tracer experiments (hands-on lab work) - Build a model of the system in CADET (Python-based) - Adapt the model with chromatographic columns

Kontakt: f.eilts@tum.de