Does exercise affect biomarkers of ageing? (BSc Thesis)

17.11.2025, Abschlussarbeiten, Bachelor- und Masterarbeiten

Physical activity is widely recognised as a key determinant of good health and reduced mortality. However, whether physical activity directly slows the biological ageing process remains uncertain.

Recent advances in ageing research have identified molecular and physiological biomarkers such as DNA methylation clocks, telomere length, and transcriptomic signatures that can serve as indicators of biological age. The aim of this thesis is to systematically review the current scientific literature to determine whether physical activity can slow or reverse biological ageing. By synthesising evidence from human and animal studies, this project seeks to clarify the extent to which regular physical activity influences molecular ageing pathways and to identify methodological challenges and research gaps in this emerging field.

Kontakt: henning.wackerhage@tum.de