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Sitemap > Bulletin Board > Diplomarbeiten, Bachelor- und Masterarbeiten > Systematic review of stimuli and exercise modes that increase the expression of glycolytic genes in skeletal muscle
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BSc Thesis

Systematic review of stimuli and exercise modes that increase the expression of glycolytic genes in skeletal muscle

19.07.2022, Diplomarbeiten, Bachelor- und Masterarbeiten

Glycolysis is a metabolic pathway that converts glucose or its storage form glycogen into pyruvate which in turn is used to synthesize lactate or enters mitochondria for oxidative phosphorylation. In addition, glycolysis is a feeder pathway for anabolic reactions such as nucleotide or non-essential amino acid synthesis. Sprinters and middle-distance runners aim to increase their glycolytic capacity through specific training and a high expression of glycolytic enzymes could potentially be beneficial in diabetes mellitus patients, as it may increase the capacity to utilize glucose. Whilst the regulation of muscle protein synthesis after resistance exercise and mitochondrial biogenesis after endurance exercise is now partially understood, we know far less about the stimuli and types of exercise that regulate the expression of glycolytic enzymes in skeletal muscle. The aim of the proposed project is therefore to conduct a systematic review to answer the research question „What stimuli or exercise interventions significantly increase the expression or protein abundance of glycolytic enzymes?“ In addition, you will use the MetaMex online database and do further database searches to learn more about the expression of glycolytic enzymes and e.g. muscle fibre type differences. We aim to publish this work.

Kontakt: henning.wackerhage@tum.de