PhD Student position in immunology

31.12.2023, Wissenschaftliches Personal

A PhD student position is offered as part of the CRC 1054 "Control and plasticity of cell-fate decisions in the immune system (https://www.sfb1054.med.uni-muenchen.de) in the Department of Infection Immunology headed by Prof. Christina Zielinski at the Leibniz-HKI. The department of Infection Immunology addresses fundamental questions about the mechanistic basis of the human immunological memory. We investigate T-cell communication with the local tissue microenvironment in settings of infections, autoimmunity and cancer. This research has unraveled several novel T-cell functions and immunomodulatory factors (Almeida et al., Science Immunology 2022; Matthias et al. Science Transl Med 2019 & J Clin Invest 2020, Chao et al. Nat Immunol, 2023). The department uses novel cutting-edge technologies in the area of high-dimensional single-cell analysis (scRNAseq, Spectral flow cytometry) to translate fundamental insights into translational applications for human health and disease. The prospective candidate will have the opportunity to investigate the regulation of human tissue resident T-cells and their crosstalk with the microenvironment in solid organ transplantation and cancer.

Requirements:
• A master's degree in life sciences or computational biology or MD degree
• Experience in the field of immunology. Experience in flow cytometry, cell culture and in high-dimensional single-cell data analysis and programming skills are a plus
• Very good communication and writing skills
• Organizational skills and meticulous experimentation and analysis practices
• Great enthusiasm for translational science

We offer:
• A modern workplace in a brand-new building, with top equipment (Cytek Aurora Spectral Analyser and Sorter, single-cell sequencing etc.)
• A cutting-edge highly funded research project in immunology
• A highly dynamic international young team in a thriving research environment in a Leibniz Institute with many large collaborative projects such as the Cluster of Excellence Balance of the Microverse
• Participation in structured mentoring programs.

The successful candidate will be hosted in the department of Infection Immunology of Prof. Christina Zielinski. The Leibniz-HKI is embedded in the outstanding scientific environment of the Beutenberg Campus in Jena providing state-of-the-art research facilities and a highly integrative network of life science groups and is imbedded in the Excellence Cluster "Balance of the Microverse". We offer a multifaceted scientific project with excellent technical facilities, a place in a dynamic, committed team, as well as strong scientific collaborations.
Salary is paid according to German TV-L (TV-L 13 salary agreement for public service employees). As an equal opportunity employer, the Leibniz-HKI is committed to increasing the percentage of female scientists and therefore especially encourages them to apply.
Further information:
Prof. Dr. med. Christina Zielinski | www.zielinskilab.com

Applications:
Complete applications in English should include a cover letter, a CV containing a complete list of publications, a brief statement of research experiences, the addresses of two possible referees, and should be submitted to christina.zielinski@leibniz-hki.de.

Kontakt: Christina.zielinski@leibniz-hki.de