Bioinformatik

Bioinformatician (m/w/d) in Vollzeit

18.04.2024, Wissenschaftliches Personal

The Molecular Pathology Diagnostic Laboratory at the Institute of Pathology at the Technical University of Munich is one of the leading diagnostic NGS labs in Germany, partner of the Comprehensive Cancer center Munich TUM and, together with the clinical disciplines, supports the Molecular Tumor Board at the Klinikum rechts der Isar.

Who are we?
The Molecular Pathology Diagnostic Laboratory at the Institute of Pathology at the Technical University of Munich is one of the leading diagnostic NGS labs in Germany, partner of the Comprehensive Cancer Center Munich TUM (CCCMTUM) and, together with the clinical disciplines, supports the Molecular Tumor Board at the Klinikum rechts der Isar.
The field of molecular pathology has entered diagnostic pathology in recent years and now represents an important subfield of pathological diagnostics. Molecular pathology helps in making accurate diagnoses and therapy decisions. In
this context, it forms the basis of so-called "personalized medicine", in which the patient can be offered an individually adapted therapy for certain tumor diseases/defects based on an ascertained molecular profile and after an
interdisciplinary decision, e.g. in a so-called molecular tumor board. The core of the analyses is massive parallel sequencing ("Next Generation Sequencing"), with which in principle almost all nucleic acid analyses can be performed.
The bioinformatics interpretation of these genomic and transcriptomic data as well as the potential therapeutic consequences are gaining enormous importance with the increasing size of the data sets in this context.

Requirements
The candidate should have a degree in Bioinformatics, Computational Biology, Machine Learning or related fields with
a demonstrated track record in:
- experience working with at least one “omics” type (e.g. DNAseq, RNAseq, metabolomics, spatial transcriptomics),
- preference will be given to candidates with experience in integration of multi-omics data, and/or somatic variant
calling
- programming experience in scripting languages such as Python/Perl and/or in statistical program R is a necessity,
- ability to work efficiently in a Linux command-line environment is a requirement,
- ability to learn new tools and content quickly and independently
- ability to work in a collaborative environment,
- excellent communication skills in both written and spoken English or German are required.

What you’ll be working on:
The ideal candidate will work in an interdisciplinary team, contributing it’s skills on both clinical and research aspects of bioinformatics. The tasks to be performed are:
- developing and applying methods for processing, analyzing, and interpreting multi-omics data.
- maintaining and/or developing new functionality for bioinformatics pipelines to analyze and visualize multi-omics data.
- conducting research in the fields of cancer biology with the aim of identifying potential diagnostic indicators in
cancer detection or development of targeted therapies.
- supporting the team in analyzing WGS/WES/targeted data for diagnostics.

Contract Duration and Other Benefits:
- two-year full time contract with compensation based on skill and experience level (TV-L E13)
- partial home office possible
- The position is suitable for people with sever disabilities. Given equivalent qualifications (same suitability, ability and professional performance), applications by persons with disabilities will be preferentially considered.

How to apply:
Interested applicants should send their CV and a cover letter with the contact of at least one referee (related to the field
of the job) to mihaela.thiele@tum.de with CC to shounak.chakraborty@tum.de and nicole.pfarr@tum.de.
Deadline: 31.05.2024

Kontakt: renate.krummeck@tum.de