Vortrag
Protein-protein and protein-ligand interactions: combining large datasets with structural knowledge
Mittwoch 23.05.2012, 18:00 - 19:00
Vortragender
Dr. Olga Kalinina, Max Planck Institute for Informatics, Saarbrücken
Bioinformatics Colloquium
The growing wave of data on protein sequences and structures poses new questions and opens new prospects for computational biology. In this talk, we will consider several examples of how a structural bioinformatics study can profit from using large datasets. First, we present a novel approach to predicting of drug-target interactions that makes use of all available protein-ligand complexes. In another study, we use a large body of known sequences for the HIV capsid protein to gain insight into quaternary arrangement of the HIV capsid structure.
Veranstalter
TUM, LMU, Recess
Ansprechpartner
Prof. Hans-Werner Mewes, TU München